Acute Myelogenous Leukaemia


Let’s understand what leukemia is actually?

Leukemia is a disorder of the white blood cells characterized by malignant transformation of blood forming cells primarily in the bone marrow and in certain conditions in the lymph nodes, resulting in increased number of primitive white cells (blast cells) in the bone marrow. It can be divided into acute and chronic leukemia with further subtypes.

Acute myelogenous leukemia comes under one of the four types of leukemia. It occurs in adult age mainly in between 15-40 years and it comprises 20% of childhood leukemia.

 

CAUSE:

 

Acute myelogenous leukemia occurs due to failure of cell maturation after proliferation of stem cells, leading to accumulation of primitive cells (blasts cells) in the marrow space at the expense of normal haemopoietic elements. Eventually, these proliferative cells gain entry into the circulation.

 

ETIOLOGY:

 

RISK FACTORS:

 

SYMPTOMS:

 

CLASSIFICATION OF AML ACCORDING TO WHO:

 

DIAGNOSIS:

 

TREATMENT:

 

SUPPORTIVE TREATMENT:

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